Biomedical Imaging Center

BIC Research

X-Ray Imaging

The evolution of civilization is driven by the need for extending our capabilities. A most important way for us to sense the world is by vision. Biomedical imaging systems outperform our natural vision and become indispensible “eyes” in the fields of biology and medicine. A fascinating puzzle in history was how to achieve “an inner vision” of opaque objects. X-ray computed tomography (CT) is the first imaging modality to enable non-destructive sectional or volumetric image reconstruction of an object from x-ray shadows. Since the introduction of x-ray CT, biomedical imaging technology has been under rapid development for predictive, preventive and personalized medicine and should dramatically improve our longevity and quality of life. Our currently funded projects target x-ray CT and optical molecular tomography, multimodality and emerging possibilities.    More...

Optical Imaging

Translational research is transforming the way science has operated for decades, bridging the gaps that separate basic scientists and clinical researchers. To improve human health, scientific discoveries must be translated into practical applications. Such discoveries typically begin at “the bench” with basic research, in which scientists study disease at a molecular or cellular level, and then progress to the clinical level, or the patient’s “bedside”.

Optical imaging technologies, which exploit the physics of optical propagation in tissue, add many important advantages to the imaging options currently available to physicians and researchers.    More...

Magnetic Resonance Imaging (MRI)

Multimodality imaging systems such as positron emission tomography-computed tomography (PET-CT) and MRI-PET are widely available, but a simultaneous CT-MRI instrument has not been developed. Synergies between independent modalities, e.g., CT, MRI, and PET/SPECT can be realized with image registration, but such postprocessing suffers from registration errors that can be avoided with synchronized data acquisition. The clinical potential of simultaneous CT-MRI is significant, especially in cardiovascular and oncologic applications where studies of the vulnerable plaque, response to cancer therapy, and kinetic and dynamic mechanisms of targeted agents are limited by current imaging technologies.   More...