Translational research is transforming the way science has operated for decades, bridging the gaps that separate basic scientists and clinical researchers. To improve human health, scientific discoveries must be translated into practical applications. Such discoveries typically begin at “the bench” with basic research, in which scientists study disease at a molecular or cellular level, and then progress to the clinical level, or the patient’s “bedside”.
Optical imaging technologies, which exploit the physics of optical propagation in tissue, add many important advantages to the imaging options currently available to physicians and researchers. Optical imaging and spectroscopy technologies provide dynamic molecular, structural and functional imaging with the potential to expand clinical opportunities for screening, early disease detection, diagnosis, image guided intervention, safer therapy, and monitoring of therapeutic response.
Founded in 2007, Our goal is to develop quantitative thick-tissue optical imaging platforms for pre-clinical and clinical applications. We focus on three main areas:
- Design new optical tomographic imaging instrumentation;
- Develop new reconstruction algorithms for quantitative volumetric imaging;
- Investigate optimal experimental and theoretical parameters for functional, molecular, and dynamical optical imaging.