K. V. Lakshmi

K. V. Lakshmi

Associate Professor, Scientific Director, Baruch '60 Center For Biochemical Solar Energy Research

Physical Chemistry, Inorganic Chemistry, Biochemistry and Biophysical Chemistry, Bioinorganic Chemistry, Cheminformatics and Computational Chemistry, Polymers, Materials and Energy, Green Chemistry and Sustainability, Solar Energy Conversion, Natural and Artificial Photosynthesis

Dr. Lakshmi is an Associate Professor in the Department of Chemistry and Chemical Biology and Scientific Director of the Baruch ’60 Center for Biochemical Solar Energy Research at Rensselaer. She is trained in the development and application of advanced biophysical spectroscopy at Brandeis, the Francis Bitter Magnet Laboratory at MIT, and Yale University. She is recognized worldwide as a leader in the current generation of young physical chemists and biophysicists for her research on the development of state-of-the-art multi-frequency multi-dimensional pulsed EPR spectroscopy, solids NMR spectroscopy and electron-nuclear spectroscopy methods. In fact, she is one of very few researchers around the world with expertise and training in developing both advanced solids NMR and pulsed multi-frequency EPR spectroscopy methods. She applies her advanced training and knowledge in magnetic resonance spectroscopy, molecular genetics, biochemistry, inorganic and bioinorganic chemistry, computational chemistry and in situ observation of light-driven intermediates to address the molecular mechanisms of solar energy conversion in natural and artificial photosynthetic systems.

Dr. Lakshmi is the recipient of several awards for her research including the Bioenergetics Award by the American Biophysical Society for outstanding contributions in the field of membrane bioenergetics, the Therese Cotton Memorial Early Career Award by the Gordon Research Conferences for excellence in photosynthesis research, and a UNESCO fellowship. She has authored over 60 peer-reviewed journal publications and is an invited speaker at numerous national and international conferences. Her current research collaborations include both academic institutions and National laboratories, such as, Argonne National Laboratory, Brookhaven National Laboratory, Pacific Northwest National Laboratory, Lawrence Berkeley National Laboratory, Yale University, MIT, Harvard University, Penn State University, University of California at Berkeley and Riverside, Temple University and the Indian Institutes of Technology at Delhi and Bombay in India. She has served as a Chair and co-Chair of leading conferences on natural and artificial photosynthesis and solar energy utilization. She has also served as a scientific consultant to biotechnology, pharmaceutical and energy industries. She is a reviewer for leading scientific journals, U. S. Department of Energy, National Science Foundation, American Chemical Society, Netherlands Organization for Scientific Research and the Biotechnology and Biological Scientific Research Council in the United Kingdom. She has held visiting appointments at Yale University, Argonne National Laboratory and University of California, Berkeley, Lawrence Berkeley National Laboratory.    

Education

http://academictree.org/chemistry/tree.php?pid=522147

Selected Publications

  • 64. B. M. Kriegel, L. C. E. Naested, G. Nocton, K. V. Lakshmi, T. D. Lohrey, R. G. Bergman and J. Arnold “Redox Initiated Reactivity of Dinuclear Niobium Imido Complexes” (2016) Inorg. Chem., Manuscript Submitted.
  • 61. J. K. Cooper, S. B. Scott, Y. Ling, J. Yang, S. Hao, Y. Li, F. M. Toma, M. Stutzmann, K. V. Lakshmi and I. D. Sharp “The Role of Hydrogen in Defining the n-Type Character of BiVO4 Photoanodes” (2016) Chem. Mat., 28, 5761-5771.
  • 60. M. Ziegler, D. S. Levine, K. V. Lakshmi and T. D. Tilley “Aryl Group Transfer from Tetraarylborato Anions to an Electrophilic Dicopper(I) Center and Mixed-Valence μ -Aryl Dicopper(I,II) Complexes” (2016) J. Amer. Chem. Soc., 138, 6484-6491.
  • 59. E. Ganapathi, H. Kalita, G. G. Theophall, K. V. Lakshmi and M. Ravikanth “Synthesis and Quantum Mechanical Studies of Mixed B(III) and P(V) Complexes of Meso-Triaryl 25-Oxasmaragdyrins” (2016) Chem. Eur. J., 22, 9699-9708.
  • 58. I. Silva, B. Jagannathan, J. H. Golbeck and K. V. Lakshmi “Elucidating the Design Principles of Photosynthetic Electron-transfer Proteins by Site-directed Spin Labeling EPR Spectroscopy” (2015) Biochim. Biophys. Acta, Manuscript in Press, DOI: 10.1016/j.bbabio.2015.08.009.
  • 54. C. S. Coates, S. Milikisiyants, R. Chatterjee, M. Whittaker, J. Whittaker and K. V. Lakshmi “Superoxidized Mn(III)Mn(IV) Catalase as a Model for the Oxygen Evolving Complex of Photosystem II” (2015) J. Phys. Chem. B, 119, 4905. (Featured Cover Article)
  • 50. R. Chatterjee, C. S. Coates, A. M. Meenaghan, S. Milikisiyants, C-I. Sophia Lee, A. Wagner, O. G. Poluektov and K. V. Lakshmi “Snapshots of Biological Proton-Coupled Electron Transfer: Electron-Nuclear Double Resonance Spectroscopy of Tyrosine Intermediates in Photosystem II” (2013) Biochemistry, 52, 4781.
  • 49. S. Milikisiyants, R. Chatterjee, C. S. Coates, F. M. K. Koua, J-R. Shen and K. V. Lakshmi “The Structure and Activation of Substrate Water Molecules in the S2 State of Photosystem II Studied by Hyperfine Sublevel Correlation Spectroscopy” (2012) Energy Environ. Sci., 5, 7747.
  • 48. R. Chatterjee, S. Milikisiyants and K. V. Lakshmi “Two-Dimensional 14N HYSCORE Spectroscopy of the Coordination Geometry of Ligands in Dimanganese Di-μ-oxo Mimics of the Oxygen Evolving Complex of Photosystem II” (2012) Phys. Chem. Chem. Phys., 14, 7090.
  • 45. N. Srinivasan, R. Chatterjee, S. Milikisiyants, J. H. Golbeck and K. V. Lakshmi High-Resolution 1H and 14N Imaging of the Phylloquinone Binding Pocket in Photosystem I Using Two-Dimensional Hyperfine Sub-Level Correlation Spectroscopy (2011) Biochemistry, 50, 3495.
  • 62. T. Chatterjee, G. G. Theophall, K. Ishara Silva, K. V. Lakshmi* and M.Ravikanth* Synthesis and Quantum Mechanical Studies of a Highly Stable Ferrocene-Incorporated Expanded Porphyrin (2016) Inorg. Chem., 55, 6873–6881.
  • 57. H. Kalita, W-Z. Lee, G. Theophall, K. V. Lakshmi and M. Ravikanth “Formation of Stable B, C, N, O and P Atoms Containing a Seven-Membered Heterocycle inside Smaragdyrin Macrocycle” (2015) Chem. Eur. J., 21, 11315.
  • 56. K. Yadav, B. R. Mehta, K. V. Lakshmi and J. P. Singh “Tuning the Wettability of Indium Oxide Nanowires: The Effect of Oxygen Related Defects” (2015) J. Phys. Chem. C, 119, 16026.
  • 46. R. Chatterjee, C. Coates, S. Milikisiyants, O. G. Poluektov and K. V. Lakshmi “The Structure and Function of Quinones in Biological Solar Energy Transduction: A High-Frequency D-Band EPR Spectroscopy Study of Model Benzoquinones” (2011) J. Phys. Chem. B, 116, 676.
  • 55. A. Mishra, K. V. Lakshmi and L. Huang “Eco-friendly Synthesis of Metal Dichalcogenides Nanosheets and Their Environmental Remediation Potential Driven by Visible Light” (2015) Sci. Reports, 5, 15718.
  • 53. S. Milikisiyants, R. Chatterjee, C. S. Coates, F. M. K. Koua, J-R. Shen and K. V. Lakshmi “The Structure and Activation of Substrate Water Molecules in Sr2+-substituted Photosystem II” (2014) Phys. Chem. Chem. Phys., 16 (38), 20834.
  • 52. K. V. Lakshmi, C. S. Coates, S. Smith and R. Chatterjee “Radical Intermediates in Type II Reaction Centers” (2014) “The Biophysics of Photosynthesis”, Eds. J. H. Golbeck and A. van der Est, Springer, NY, pp. 299.
  • 51. C. S. Coates, J. Ziegler, J. Good, K. Manz, B. Kang, S. Milikisiyants, R. Chatterjee, S. Hao, J. H. Golbeck and K. V. Lakshmi “A Cyclic Voltammetry, EPR and Hyperfine Sub-Level Correlation (HYSCORE) Spectroscopy Study of Model Naphthoquinones” (2013) J. Phys. Chem. B, 117, 7210.
  • 47. S. Milikisiyants, R. Chatterjee and K. V. Lakshmi "Two-Dimensional 1H HYSCORE Spectroscopy of Dimanganese Di-μ-oxo Mimics of the Oxygen Evolving Complex of Photosystem II" (2012) J. Phys. Chem. B, 115, 12220.
  • 44. R. Chatterjee, S. Milikisiyants, C. Coates, and K. V. Lakshmi High-Resolution Two-Dimensional 1H and 14N Hyperfine Sub-Level Correlation (HYSCORE) Spectroscopy of the Primary Quinone of Photosystem II (2011) Biochemistry, 50, 491.
  • 43. S. Milikisiyants, R. Chatterjee, A. Weyers, A. Meenaghan, C. Coates and K. V. Lakshmi The Ligand Environment of the S2 State of Photosystem II: A Study of the Hyperfine Interactions of the Tetranuclear Manganese Cluster by 14N 2D HYSCORE Spectroscopy (2010) J. Phys. Chem B., 114, 10905.
  • 42. B. Jagannathan, S. Dekat, J. H. Golbeck and K. V. Lakshmi, A Site-Directed Spin Labeling EPR Study of the Assembly of the PsaC Subunit in Photosystem I (2010) Biochemistry, 49, 2398.
  • 41. Mukesh Kumar, B. R. Mehta, V. N. Singh, R. Chatterjee, S. Milikisiyants, K. V. Lakshmi and J. P. Singh The Role of the Stoichiometry of Indium and Oxygen on the Gas Sensing Properties of Indium Oxide Nanostructures (2010) Appl. Phys. Lett. 96 (12), 123114.
  • 40. A. M. Weyers, R. Chatterjee, S. Milikisiyants and K. V. Lakshmi Structure and Function of Quinones in Biological Solar Energy Transduction: A Differential Pulse Voltammetry, EPR and Hyperfine Sublevel Correlation (HYSCORE) Spectroscopy Study of Model Benzoquinones. (2009) J. Phys. Chem. B 113 (46), 15409.
  • 39. M. Kumar, R. Chatterjee, S. Milikisiyants, B. R. Mehta and J. P. Singh, F. Singh and K. V. Lakshmi EPR spectroscopy of Hydrogen Defects in Tuned Indium Oxide Nanostructures (2009) Appl. Phys. Lett., 95, 13102.
  • 38. M. Kumar, V. N. Singh, B. R. Mehta, F. Singh, J. P. Singh and K. V. Lakshmi Origin of Photoluminescence in Indium Oxide Octahedron Structures: The Role of Oxygen Vacancies (2008) Appl. Phys. Lett. 92, 171907.
  • 37. Ritika Uppal, K. V. Lakshmi and Ann M. Valentine Isolation and Characterization of the Iron-Binding Properties of a Primitive Monolobal Transferrin from Ciona intestinalis (2008) J. Biol. Inorg. Chem. 13, 873.
  • 36. C.-I. Lee, K. V. Lakshmi and G. W. Brudvig EPR Studies of the Functional Role of Ca2+Ions in the Oxygen-Evolving Complex of Photosystem II by Metal Ion Substitution (2007) Biochemistry 46, 3211.
  • 35. R. Uppal, C. D. Incarvito, K. V. Lakshmi and A. M. Valentine Aqueous Spectroscopy and Redox Properties of Carboxylate-Bound Titanium (2006) Inorg. Chem. 45, 1795.
  • 34. O. G. Poluektov, S. V. Paschenko, L. M. Utschig, K. V. Lakshmi and M. C. Thurnauer Direct Evidence for Bidirectional Electron Transfer in Photosystem I (2005) J. Amer. Chem. Soc. 127, 11910.