|CBIS Research Core Facilities|
The Center for Biotechnology and Interdisciplinary Studies Building (CBIS) supports several state-of-the-art Research Cores that are available to all Rensselaer faculty, staff and students and also to external academic and industrial collaborators and researchers.
CBIS Research Core Administration
Research Core Directors
Research Cores – Snapshots
The Analytical Biochemistry & Nanobiotechnology Research Core includes a Biacore 3000 (surface plasmon resonance) system, Differential Scanning Calorimeter, a fluorimeter, a small angle X-ray scattering system, a circular dichroism spectrophotometer, a UV-vis spectrophotometer, a wide-angle X-ray scattering system and an array of dynamic and static light scattering instruments.
The BioImaging Research Core features a Bruker 600 MHz Wide-Bore Solid-State 14T NMR and Multichannel Heteronuclear Microimaging Spectrometer and a Bruker Pharmascan 16cm 7T Horizontal MRI / MRS system. The Core also integrates equipment from other Corers in imaging studies, including the CT Scanner and the MALDI-TOF/TOF spectrometer.
The BioResearch / Animal Research Core houses multiple research rodent colonies, including transgenic lines, a Zebrafish research facility and a Pharmascan Small Animal Imaging Horizontal MRI / MRS suite. Multiple suites are dedicated to neurobehavior research, circadian research, surgery, necropsy, embryology and cryopreservation, histology and quarantine monitoring.
The Cell & Molecular Biology Core laboratories offer standard tissue culture facilities, a BD FACS sorter and analyzer, an Amaxa Nucleofector 96-well Shuttle System, a GE Typhoon Trio+ Imaging system, multiple thermal cyclers and molecular analysis equipment and an RT-PCR system.
The Microbiology and Fermentation Core includes two 40 liter BioFlo fermentors, a 20 liter BioFlo fermentor, multiple centrifuges and ultracentrifuges, a French Press and an analytical ultracentrifuge.
The Microscopy Core offers multiple Zeiss confocal microscopes (equipped with lasers, multiphoton, and optical tweezer-molecular capture accessories), an Asylum Atomic Force microscope equipped with TIRF accessories and a high resolution Micro CT in vivo scanner.
The Nuclear Magnetic Resonance Core (NMR) houses an 800 MHz unit, a pair of 600 MHz spectrometers (solution and wide bore solid phase equipped with small animal imaging capabilities) and a LINUX computation cluster.
The Proteomics Research Facility offers a dedicated sample preparation and HPLC laboratory, a Bruker MALDI-TOF/TOF mass spectrometer, a Thermo LTQ-Orbitrap mass spectrometer and a Thermo TSQ mass spectrometer.
The Stem Cell Research Core is a recharge facility designed to provide equipment and training to enable stem cell research at RPI, throughout the capital district and upstate NY using existing stem cell lines.
In addition to standard laboratory equipment and facilities, CBIS contains Drosophila research rooms, numerous HPLC systems with photodiode array detectors and auto-injectors, GPC-HPLC systems, gas chromatographs with auto-injectors, a gas chromatograph-mass spectrometry system with auto-injector and mass range to 1200 amu, an Agilent 110 series LC/MSD trap ESI mass spectrometer, a Pharmacia FPLC system, a Beckman capillary electrophoresis system, uv-vis-fluorescence plate readers, numerous uv-vis spectrophotometers, spectrofluorophotometers, Cartesian MicroSys 160-SQ microarrayers, an Axon microarray scanner, a Packard liquid scintillation counter, TLC chromatography systems, a Pharmacia Phast Electrophoresis apparatus, a Jasco optical polarimeter, a Mettler pH-Stat, a Karl-Fischer Titrator, an Eppendorf thermocycler, a Coulter Counter Model ZF, epifluorescence microscopes, Nikon inverted microscopes and a Zeiss Axiovert35 fluorescent inverted microscope with an Optimas image analysis system.