CBIS Facilities
Research Faculty at CBIS

MMI Laser Microdissection/Optical Tweezers

Optical tweezers are capable of measuring picoNewton forces involved in single molecule dynamics and interactions (e.g. proteins & nucleic acids), while the laser microdissection setup can isolate tissue, single cells, or even submolecular structures (e.g. chromosomes); isolated material can then be prepared for genomic or proteomic analysis.

The MMI CellCut/CellManipulator system is mounted on an Olympus IX-71 microscope with a motorized stage and CCD camera. Differential Interference Contrast and widefield fluorescence modalities are available. Laser microdissection is performed with a 355nm laser; a touch screen makes selecting regions of interest for microdissection simple. The optical tweezers use a 1064 YAG infrared laser with 3W trapping power that can be split (time-share mode) to trap up to 10 different objects. Dual quadrant detectors are available for detection.

Rates & Fees: 

Rates are hourly and are subject to change without further notice.  
Valid through July 31, 2019.

  RPI Users External Nonprofit External Industry External Industry Partners
Standard $24 $39 $78 $70
Assisted $48 $78 $156 $140
Training $62 $100 $201 $181
Personnel Time $52 $84 $168 $152