Library Preparation and Bioinformatics Analysis
- Genomic: whole genome DNA-Seq and microbial metagenomics sequencing.
- Transcriptomic: strand-specific RNA-Seq and small RNA-Seq.
- Epigenomic: whole genome methyl-Seq and ChIP-Seq.
- Bioinformatic: gene expression profiling, genome/transcriptome assembly and annotation, SNP/SV detection, population genetics studies and metagenomics analysis.
Equipment Rates & Fees
Services
| Service | Unit | RPI User | External Nonprofit | External Industry | Industrial Partners |
|---|---|---|---|---|---|
| Illumina RNA/DNA Library prep | per sample | $150 | $247 | $494 | $444 |
| Nanopore RNA/DNA library preparation | per sample | $236 | $388 | $776 | $699 |
| Bioanalyzer | per chip | $63 | $104 | $207 | $197 |
| Qubit | per sample | $3.50 | $6 | $12 | $10 |
| Gel Electrophoresis | per gel | $14 | $23 | $46 | $41 |
| PCR-QC | per sample | $14 | $23 | $46 | $41 |
Analysis
| Category | Service | Unit | RPI User | External Nonprofit | External Industry | External Industry Partner |
|---|---|---|---|---|---|---|
| Data QC and alignment | Barcode deconvolution, quality assessment and read clean-up | per sample | $20 | $33 | $66 | $60 |
| Reference genome mapping | per sample | $31 | $51 | $102 | $92 | |
| RNA-Seq | RNA-Seq batch analysis (≤20 samples) | per run | $1982 | $3260 | $6521 | $5869 |
| Gene expression profilling per sample | per sample | $31 | $51 | $102 | $92 | |
| Differential expression analysis | per project | $257 | $423 | $846 | $762 | |
| DNA-Seq | Prokaryotic DNA-Seq batch analysis (≤20 samples) | per run | $2230 | $3668 | $7337 | $6603 |
| Eukaryotic DNA-Seq batch analysis (≤20 samples) | per run | $2849 | $4687 | $9373 | $8436 | |
| Prokaryotic genomic variant calling | per sample | $31 | $51 | $102 | $92 | |
| Eukaryotic genomic variant calling | per sample | $65 | $107 | $214 | $193 | |
| GBS variant calling | per sample | $31 | $51 | $102 | $92 | |
| Variant quality assessment and filtering | per project | $516 | $849 | $1698 | $1529 | |
| Small RNA-Seq | Small RNA-Seq batch analysis (≤20 samples) | per run | $1982 | $3260 | $6521 | $5869 |
| Small RNA-Seq peak calling | per sample | $31 | $51 | $102 | $92 | |
| Differential expression analysis | per project | $257 | $423 | $846 | $762 | |
| Epigenetic: protein-DNA interaction | ChIP-Seq batch analysis (≤20 samples) | per run | $2849 | $4687 | $9373 | $8436 |
| ChIP-Seq analysis | per sample | $65 | $107 | $214 | $193 | |
| TF location and motif analysis | per project | $516 | $849 | $1698 | $1529 | |
| Genome | Prokaryotic genome annotation | per genome | $31 | $51 | $102 | $92 |
| Prokaryotic genome assembly | per genome | $31 | $51 | $102 | $92 | |
| Prokaryotic transcriptome assembly | per genome | $31 | $51 | $102 | $92 | |
| Population | Population structure analysis | per project | $2577 | $4240 | $8479 | $7632 |
| Population genetics parameters | per project | $2577 | $4240 | $8479 | $7632 | |
| Genome wide association analysis | per project | $2577 | $4240 | $8479 | $7632 | |
| Custom | Custom downstream analysis | per hour | $70 | $115 | $168 | $152 |
| Server | Server monthly fee | per account | $183 | $302 | $603 | $543 |
| RPI Users | External Nonprofit | External Industry | External Industry Partners | |
|---|---|---|---|---|
| Personnel Time | $70 | $115 | $230 | $207 |
Valid through July 31, 2024. Rates are hourly unless specified otherwise and are subject to change without further notice.
Required Acknowledgement and Authorship
Please acknowledge the CBIS Core Facilities in all publications and grant applications where our equipment and/or personnel have facilitated the work. These acknowledgements are very important because documenting our contributions helps to ensure that the resources of the Core Facilities are sustainable.
- Equipment: If you used Core Facility equipment, please note this in the Materials and Methods. e.g., Thermogravimetric analysis was carried out using a TA Instruments TGA-Q50 (Rensselaer CBIS Analytical Biochemistry Core Facility).
- Personnel: Please consider including CBIS personnel as co-authors on your publications when they have made a significant intellectual contribution to the research. Include CBIS Core Facility directors or staff as co-PI or co-investigators in grant applications when they provide a significant contribution to the grant proposal and scientific/intellectual leadership for the proposed work. Please follow these guidelines: ABRF Recommended Guidelines for Authorship on Manuscripts. Also, our Core Facility personnel always appreciate when they are mentioned in the Acknowledgements section of publications.
- Required Funding Authorization Form: Rensselaer researchers must fill out the CBIS Cores Authorization Form (PDF) to use the CBIS Core Facilities.
