Bruker 600 MHz Wide-Bore Spectrometer and MRI Scanner
The Avance III 600MHz/14T widebore instrument is well equipped for performing solid-state NMR, MRI, and diffusion studies. For solid-state NMR, high power RF and gradient amplifiers, magic angle spinning unit, and multiple accessories for operation over a wide temperature range including very low temperatures are available. Probes options include
- 4mm HXY MAS solids probe, where X and Y are broad band tunable RF channels
- 3.2mm E-free H,C,N/P MAS probe, optimized to greatly reduce sample heating of biomaterials and has an RF channel that is switchable between 15N and 31P
- 5mm TBI HCXD (where X is broadband tunable) solution probe with triple axis gradients
- 5mm TXI HCND probe with triple axis gradients
- 15 and 25mm volume TR coils, animal handling unit, inhaled anesthesia, and biometric monitoring/triggering equipment for microMRI applications
The Solid-State NMR is a vital tool at RPI and is being used to quantify, characterize, and further develop novel materials, devices, and molecular systems, including synthesis and assembly of molecular systems at the interface of biology and nanotechnology, diabetes related changes in bone structure at atomic resolution, functionalized polymers, structural studies of membrane proteins (constitute over 30% of all eukaryotic proteins, but <0.5% of known protein structures) and insoluble and plaque forming protein aggregates such as those involved in Alzheimer’s and Parkinson’s diseases.
Microimaging/MRS provide exceptional sensitivity for imaging and MRS (spatial resolved NMR spectroscopy) studies of organs, tissue samples, and materials approaching μm range resolution for many resonator/gradient combinations (far exceeding resolution limits achievable by standard horizontal bore imaging systems).
| RPI Users | External Not for Profit | External Industry | External Industry Partners | |
|---|---|---|---|---|
| Standard | $9.3 | $15.2 | $30.5 | $27.5 |
| Assisted | $13.9 | $22.8 | $45.7 | $41.1 |
| Training | $85 | $140 | $210 | $189 |
| RPI Users | External Nonprofit | External Industry | External Industry Partners | |
|---|---|---|---|---|
| Personnel Time | $73 | $120 | $240 | $216 |
Valid through July 31, 2025. Rates are hourly unless specified otherwise and are subject to change without further notice.
Required Acknowledgement and Authorship
Please acknowledge the CBIS Core Facilities in all publications and grant applications where our equipment and/or personnel have facilitated the work. These acknowledgements are very important because documenting our contributions helps to ensure that the resources of the Core Facilities are sustainable.
- Equipment: If you used Core Facility equipment, please note this in the Materials and Methods. e.g., Thermogravimetric analysis was carried out using a TA Instruments TGA-Q50 (Rensselaer CBIS Analytical Biochemistry Core Facility).
- Personnel: Please consider including CBIS personnel as co-authors on your publications when they have made a significant intellectual contribution to the research. Include CBIS Core Facility directors or staff as co-PI or co-investigators in grant applications when they provide a significant contribution to the grant proposal and scientific/intellectual leadership for the proposed work. Please follow these guidelines: ABRF Recommended Guidelines for Authorship on Manuscripts. Also, our Core Facility personnel always appreciate when they are mentioned in the Acknowledgements section of publications.
- Required Funding Authorization Form: Rensselaer researchers must fill out the CBIS Cores Authorization Form (PDF) to use the CBIS Core Facilities.
