Cell and Molecular Biology

The Cell and Molecular Biology Core Facility provides highly advanced molecular biology instruments to support experimental demands ranging from cell and tissue culture techniques to advanced cell transfection and genomics applications capabilities.  The instruments include real-time PCR machines, imaging blots, gels and multi-well trays with fluorescence and bioluminescence capabilities. The Core Facility is also equipped with a tissue and cell culture facility for BSL-2+ research that includes CO2 incubators, refrigerators, environmental rooms, centrifuges, water baths, and inverted microscope for culture analysis.

Contact Information:
Sergey Pryshchep, Ph.D.
Cell & Molecular Biology Research Core Director
518-276-3456
pryshs@rpi.edu

 

Amaxa Nucleofector
Amaxa Nucleofector
The Amaxa nucleofector uses a novel non-viral transfection technology to introduce nucleic acids (both DNA and RNA) into stem cells, primary cells, and cell lines that are difficult to transfect.
Open laboratory instrument with lid raised next to a laptop on a lab bench.
Azure Biosystems, Sapphire FL, biomolecular, IS4000
The Sapphire FL is the second-generation Sapphire platform and an advanced biomolecular imaging system designed for maximum flexibility and performance.
ChemiDoc XRS+
Biorad ChemiDoc XRS+ Imager
Used for imaging a varied range of applications including: Western blotting, gel electrophoresis, DNA/RNA gel electrophoresis densitometry, etc.
Image of two pieces of equipment both sitting on lab tables.
Roche LightCycler 480 RT-PCR and Step-One Plus real-time PCR
The LightCycler ®480 Real-Time PCR System includes interchangeable silver thermal block cycler unit. Users can flexibly switch between 96- and 384-mulitiwell plate formats, or choose between multiwell plates. The StepOnePlus System supporting the full range of Applied Biosystems TaqMan® Assays, while providing ease of use.
Tissue Culture Facility
A full-service cell culture shared resource
X-Ray Film Developer
Membership rates are per year per group and are subject to change without further notice.

Required Acknowledgement and Authorship

Please acknowledge the CBIS Core Facilities in all publications and grant applications where our equipment and/or personnel have facilitated the work. These acknowledgements are very important because documenting our contributions helps to ensure that the resources of the Core Facilities are sustainable.

  • Equipment: If you used Core Facility equipment, please note this in the Materials and Methods. e.g., Thermogravimetric analysis was carried out using a TA Instruments TGA-Q50 (Rensselaer CBIS Analytical Biochemistry Core Facility).
  • Personnel: Please consider including CBIS personnel as co-authors on your publications when they have made a significant intellectual contribution to the research. Include CBIS Core Facility directors or staff as co-PI or co-investigators in grant applications when they provide a significant contribution to the grant proposal and scientific/intellectual leadership for the proposed work. Please follow these guidelines: ABRF Recommended Guidelines for Authorship on Manuscripts. Also, our Core Facility personnel always appreciate when they are mentioned in the Acknowledgements section of publications.
  • Required Funding Authorization Form: Rensselaer researchers must fill out the CBIS Cores Authorization Form (PDF) to use the CBIS Core Facilities.

Shirley Ann Jackson, Ph.D. Center for
Biotechnology and Interdisciplinary Studies

1623 15th Street

518-276-4259

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