Dynamic Light Scattering (DLS) instrument

The Dynamic Light Scattering (DLS) method measures the size of particles sus-pended in liquid by measuring temporal fluctuations in the intensity of scattered light that reflects the diffusion of the particles.

IMPORTANT NOTE: This is different from Static Light Scattering (sometimes "Multiple Angle Light Scattering") which uses the angular dependence in the intensity of scattered light to calculate the molecular weight of the particles.  

Some Applications

  • Determination of the size of nano-particles and micro-beads
  • Determination of Critical Micelle Concentration
  • Monitoring Protein Complex Formation in Solution
  • Vesicle Size Distribution Analysis
  • Thermal Dissociation and Denaturation
  • Protein Purification Confirmation
  • Liposome Characterization

The term "Batch" in the instrument name means that it makes measurements one sample at a time in cuvettes. It is crucial for these measurement that samples be completely free of dust (and other irrelevant particles). Ensuring that samples are dust-free is often the most crucial aspect of sample preparation.

Manufacturer: Wyatt DynaPro Titan Batch
Equipment Rates & Fees
 RPI UsersExternal NonprofitExternal IndustryExternal Industry Partners
 RPI UsersExternal NonprofitExternal IndustryExternal Industry Partners
Personnel Time$70$115$230$207

Valid through July 31, 2024. Rates are hourly unless specified otherwise and are subject to change without further notice.

Required Acknowledgement and Authorship

Please acknowledge the CBIS Core Facilities in all publications and grant applications where our equipment and/or personnel have facilitated the work. These acknowledgements are very important because documenting our contributions helps to ensure that the resources of the Core Facilities are sustainable.

  • Equipment: If you used Core Facility equipment, please note this in the Materials and Methods. e.g., Thermogravimetric analysis was carried out using a TA Instruments TGA-Q50 (Rensselaer CBIS Analytical Biochemistry Core Facility).
  • Personnel: Please consider including CBIS personnel as co-authors on your publications when they have made a significant intellectual contribution to the research. Include CBIS Core Facility directors or staff as co-PI or co-investigators in grant applications when they provide a significant contribution to the grant proposal and scientific/intellectual leadership for the proposed work. Please follow these guidelines: ABRF Recommended Guidelines for Authorship on Manuscripts. Also, our Core Facility personnel always appreciate when they are mentioned in the Acknowledgements section of publications.
  • Required Funding Authorization Form: Rensselaer researchers must fill out the CBIS Cores Authorization Form (PDF) to use the CBIS Core Facilities.
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