Thermo Electron TSQ Quantis Plus
Speed with selectivity and sensitivity
Achieve superior acquisition speeds on the TSQ Quantis Plus mass spectrometer, which can acquire 600 SRMs/sec and when combined with a new power supply enables 5 ms polarity switching and allows the required number of data points to be acquired for expanded number of target compounds, even with ultra-high performance liquid chromatography (UHPLC) separation.
The TSQ Quantis Plus mass spectrometer delivers excellent quantitative performance in both selected reaction monitoring (SRM) and high-resolution selected reaction monitoring (H-SRM) for fit-for-purpose selectivity. The enhanced active Q2 collision cell improves product ion transmission, especially for low-mass product ions, which can increase detection efficiency.
The instrument is used for targeted qualitative and quantitative analyses of various types of compounds including carbohydrates (sulfated saccharides), Pharmaceutical and small-molecule analysis (dichlofenac, acetaminophen, rafimpin, fingolimod, resiquimod, suramin, estrogens), environmental pollutants (PFOAs, PFOSs, antibiotics, artificial sweeteners), natural products (marijuana/hemp), vitamins.
- Great versatility with mass range (2 to 3,000 m/z).
- HESI and APCI ionization modes.
- Excellent for quantitative measurements by LC/MS and LC/MS/MS methods.
- Xcalibur Software for instrument control and data analysis. (Chromeleon is optional)
- Coupled with Thermo UHPLC system operated by Xcalibur software.
- "Circulating heparin oligosaccharides rapidly target the hippocampus in sepsis potentially impacting cognitive functions", X. Zhang, X. Han, K. Xia, Y. Xu, Y. Yang, K. Oshima, S. M. Haeger, M. J. Perez, S. A. McMurtry,J. A. Hippensteel, J. A. Ford P. S. Herson, J. Liu, E. P. Schmidt, R. J. Linhardt, Proceedings of the National Academy of Sciences(USA), 116, 9208–9213, 2019.
- "The Effects of Fingolimod-Releasing ElectrospunFibers on Neurite Extension and Schwann Cell Phenotype in vitro", Ryan Gilbert, Devan L Puhl; Jessica L Funnell; Anthony R D'Amato, Jonathan Bao; Dmitri V Zagorevski, Yelena Pressman, Daniel Morone; Agnes E Haggerty, Martin Oudega, Acta Biomaterialia, in press, 2020.
- "Compositional and structural analysis of glycosaminoglycans in cell-derived extracellular matrices", J. C. Silva, M. S. Carvalho, X. Han, K. Xia, P. E. Mikael, J. M. S. Cabral, F. Castelo Ferreira, R. J. Linhardt, Glycoconjugate Journal, 36, 141–154, 2019
- "Exposure of Juncus effusus to seven perfluoroalkyl acids: Uptake, accumulation and phytotoxicity". ZhangW., ZhangD., ZagorevskiD.V., LiangY., Chemosphere, 233, 300-308, 2019.
| RPI Users | External Nonprofit | External Industry | External Industry Partners | |
|---|---|---|---|---|
| Standard | $60 | $99 | $197 | $178 |
| Assisted | $120 | $197 | $395 | $355 |
| Training | $89 | $146 | $293 | $264 |
| RPI Users | External Nonprofit | External Industry | External Industry Partners | |
|---|---|---|---|---|
| Personnel Time | $77 | $127 | $253 | $228 |
Effective August 1, 2025 through July 31, 2026. Rates are hourly unless specified otherwise and are subject to change without further notice.
Required Acknowledgement and Authorship
Please acknowledge the CBIS Core Facilities in all publications and grant applications where our equipment and/or personnel have facilitated the work. These acknowledgements are very important because documenting our contributions helps to ensure that the resources of the Core Facilities are sustainable.
- Equipment: If you used Core Facility equipment, please note this in the Materials and Methods. e.g., Thermogravimetric analysis was carried out using a TA Instruments TGA-Q50 (Rensselaer CBIS Analytical Biochemistry Core Facility).
- Personnel: Please consider including CBIS personnel as co-authors on your publications when they have made a significant intellectual contribution to the research. Include CBIS Core Facility directors or staff as co-PI or co-investigators in grant applications when they provide a significant contribution to the grant proposal and scientific/intellectual leadership for the proposed work. Please follow these guidelines: ABRF Recommended Guidelines for Authorship on Manuscripts. Also, our Core Facility personnel always appreciate when they are mentioned in the Acknowledgements section of publications.
- Required Funding Authorization Form: Rensselaer researchers must fill out the CBIS Cores Authorization Form (PDF) to use the CBIS Core Facilities.
