Thermo Electron TSQ Quantum Ultra

TSQ Quantum triple quadrupole system performsvarious types of scans including highlyselectivereactionmonitoring(H-SRM) which analyzes complex samples quickly and efficiently. It is ideal for qualitative and quantitative analyses of individual compounds and complex mixtures.

The instrument is used for targeted qualitative and quantitative analyses of various types of compounds including carbohydrates (sulfated saccharides), drugs (dichlofenac, acetaminophen, rafimpin, fingolimod, resiquimod, suramin, estrogens), environmental pollutants (PFOAs, PFOSs, antibiotics, artificial sweeteners), natural products (marijuana/hemp), vitamins.

Manufacturer: ThermoFisher Scientific
Example of results from the Thermo Electron TSQ Quantum Ultra
  • Great versatility with mass range (m/z 30–1500).
  • ESI and APCI ionization modes.
  • Excellent for quantitative measurements by LC/MS and LC/MS/MS methods.
  • Xcalibur Software for instrument control and data analysis.
  • Coupled with Agilent 1200 HPLC system operated by ChemStation software.

  • "Circulating heparin oligosaccharides rapidly target the hippocampus in sepsis potentially impacting cognitive functions", X. Zhang, X. Han, K. Xia, Y. Xu, Y. Yang, K. Oshima, S. M. Haeger, M. J. Perez, S. A. McMurtry,J. A. Hippensteel, J. A. Ford P. S. Herson, J. Liu, E. P. Schmidt, R. J. Linhardt, Proceedings of the National Academy of Sciences(USA), 116, 9208–9213, 2019.
  • "The Effects of Fingolimod-Releasing ElectrospunFibers on Neurite Extension and Schwann Cell Phenotype in vitro", Ryan Gilbert, Devan L Puhl; Jessica L Funnell; Anthony R D'Amato, Jonathan Bao; Dmitri V Zagorevski, Yelena Pressman, Daniel Morone; Agnes E Haggerty, Martin Oudega, Acta Biomaterialia, in press, 2020.
  • "Compositional and structural analysis of glycosaminoglycans in cell-derived extracellular matrices", J. C. Silva, M. S. Carvalho, X. Han, K. Xia, P. E. Mikael, J. M. S. Cabral, F. Castelo Ferreira, R. J. Linhardt, Glycoconjugate Journal, 36, 141–154, 2019
  • "Exposure of Juncus effusus to seven perfluoroalkyl acids: Uptake, accumulation and phytotoxicity". ZhangW., ZhangD., ZagorevskiD.V., LiangY., Chemosphere, 233, 300-308, 2019.
Equipment Rates & Fees
 RPI UsersExternal NonprofitExternal IndustryExternal Industry Partners
Standard$55$90$181$163
Assisted$110$181$362$326
Training$80$132$263$237
 RPI UsersExternal NonprofitExternal IndustryExternal Industry Partners
Personnel Time$70$115$230$207

Valid through July 31, 2024. Rates are hourly unless specified otherwise and are subject to change without further notice.

Required Acknowledgement and Authorship

Please acknowledge the CBIS Core Facilities in all publications and grant applications where our equipment and/or personnel have facilitated the work. These acknowledgements are very important because documenting our contributions helps to ensure that the resources of the Core Facilities are sustainable.

  • Equipment: If you used Core Facility equipment, please note this in the Materials and Methods. e.g., Thermogravimetric analysis was carried out using a TA Instruments TGA-Q50 (Rensselaer CBIS Analytical Biochemistry Core Facility).
  • Personnel: Please consider including CBIS personnel as co-authors on your publications when they have made a significant intellectual contribution to the research. Include CBIS Core Facility directors or staff as co-PI or co-investigators in grant applications when they provide a significant contribution to the grant proposal and scientific/intellectual leadership for the proposed work. Please follow these guidelines: ABRF Recommended Guidelines for Authorship on Manuscripts. Also, our Core Facility personnel always appreciate when they are mentioned in the Acknowledgements section of publications.
  • Required Funding Authorization Form: Rensselaer researchers must fill out the CBIS Cores Authorization Form (PDF) to use the CBIS Core Facilities.
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