The Center for Biotechnology and Interdisciplinary Studies Building (CBIS) supports several state-of-the-art Research Cores that are available to all Rensselaer faculty, staff and students and also to external academic and industrial collaborators and researchers. CBIS is one of the most advanced research facilities in the nation. We are also unique in our ability to generate innovation and discovery at the interface of the life sciences, physical sciences and engineering. Our interdisciplinary research teams perform fundamental, applied, and translational research.
Each core facility is led by a director holding a Ph.D. in their respective area and engaged in research. All core facilities are open to students, post-doctoral fellows and principal investigators and operate on a fee-for-service basis.
If you would like to become a user of our core facilities, the core directors will train you on the specific techniques required for your research. Our mission is to provide service, assistance, and consultation to investigators from commercial, academic, and government research laboratories.
Consider Sending Us Your Research Samples
In many instances our professional staff will accept your research samples and work with you to process and analyze them. Please contact us for more details.
CBIS Research Core Administration
- Marimar Lopez, Ph.D. - Director, Research Cores firstname.lastname@example.org
Research Core Directors
- Analytical Biochemistry - Joel Morgan, Ph.D. email@example.com
- BioImaging - Scott McCallum, Ph.D. firstname.lastname@example.org
- BioResearch / Animal Science - TBD
- Cell and Molecular Biology - Sergey Pryshchep, Ph.D. email@example.com
- Flow Cytometry- Sergey Pryshchep, Ph.D. firstname.lastname@example.org
- Genomics - Yang Bai, Ph.D. email@example.com
- Microbiology and Fermentation - Joel Morgan, Ph.D. firstname.lastname@example.org
- Microscopy - Sergey Pryshchep, Ph.D. email@example.com
- Nuclear Magnetic Resonance (NMR) - Scott McCallum, Ph.D. firstname.lastname@example.org
- Proteomics - Dmitri Zagorevski, Ph.D. email@example.com
- Stem Cell Biology - Marimar Lopez, Ph.D. - Director, Research Cores firstname.lastname@example.org
Research Cores – Snapshots
The Analytical Biochemistry & Nanobiotechnology Research Core includes equipment for characterization of biological samples (like a Jasco 815 circular dichroism spectrometer with stopped flow capabilities, GE VP-isothermal titration calorimeter, Horiba-Yobin Yvon spectrofluorimeter with lifetime measurement capabilities, Wyatt dynamic light scattering apparatus, Bruker small angle X-ray scattering system, Beckman Analytical Ultracentrifuge, Hitachi UV-visible spectrophotometer, a Rudolph polarimeter, a Shimadzu HPLC system, a Perkin-Elmer liquid scintillation counter, etc). In addition there is equipment for characterization of materials (like a TA thermogravimetric analyzer, a TA differential scanning calorimeter, a Bruker powder X-ray diffractometer, etc).
The BioImaging Research Core features a Bruker 600 MHz Wide-Bore Solid-State 14T NMR and Multichannel Heteronuclear Microimaging Spectrometer and a Bruker Pharmascan 16cm 7T Horizontal MRI / MRS system. The Core also integrates equipment from other Corers in imaging studies, including the CT Scanner and the MALDI-TOF/TOF spectrometer.
The BioResearch Core houses multiple research rodent colonies, including transgenic lines.There is easy access to the Bioimaging suite with a Small Animal MRI spectrometer. Multiple suites are dedicated to neurobehavior research, circadian research, surgery, necropsy, embryology, histology and quarantine monitoring.
The Cell & Molecular Biology Core laboratories offer standard tissue culture facilities, an Amaxa Nucleofector 96-well Shuttle System, a GE Typhoon Trio+ Imaging system, multiple thermal cyclers and molecular analysis equipment and an RT-PCR system.
The Flow Cytometry Core laboratories offer a BD FACS sorter and LSRII analyzer.
The Genomics Research Core offers NGS library preparation, sequencing and data analysis services, featuring Illumina NextSeq 550 sequencer, iSeq 100 sequencer, Agilent 2100 Bioanalyzer, Qubit 4 flurometer, Bio-Rad thermal cycler, Bio-Rad nucleic acid electrophoresis system and Dell 48-core server ‘double-helix’. Roche LightCycler and Bio-Rad ChemiDoc from CMB core are utilized for qPCR amplification and nucleic acid imaging.
The Microbiology and Fermentation Core includes two New Brunswick 40 liter BioFlo fermentors, a 20 liter BioFlo fermentor with continuous flow centrifugation capabilities, multiple centrifuges and ultracentrifuges, multiple shakers and incubators, a French Press, a nanodrop UV-vis spectrophotometer, a Klett apparatus, a sonicator, a micro-fluidizer, etc.
The Microscopy Core offers Leica TCS SP8 STED Microscope with confocal and light-sheet imaging capabilities, a Zeiss 510 confocal and multiphoton microscopes, a MMI optical tweezer and laser microdissection, an Asylum Atomic Force microscope (capable of measurements in dry and wet mode), an Olympus TIRF microscope and a Tousimis critical point dryer.
The Nuclear Magnetic Resonance Core (NMR) houses an 800 MHz unit, a pair of 600 MHz spectrometers (solution and wide bore solid phase equipped with small animal imaging capabilities) and a LINUX computation cluster.
The Proteomics Research Facility offers a Bruker MALDI-TOF/TOF mass spectrometer, a Thermo LTQ-Orbitrap mass spectrometer and a Thermo TSQ Quadrupole mass spectrometer, both coupled with micro-flow Agilent HPLC systems and a Shimadzu gas chromatograph mass spectrometer. In addition, a dedicated sample preparation laboratory is available.
The Stem Cell Research Core is a recharge facility designed to provide equipment and training to enable stem cell research at RPI, throughout the capital district and upstate NY using existing stem cell lines.
In addition to standard laboratory equipment and facilities, CBIS contains Drosophila research rooms.
Icahn School of Medicine at Mt. Sinai Research Core Facilities
Research core facilities available to CBIS investigators at The Icahn School of Medicine at Mt. Sinai in New York City. http://icahn.mssm.edu/research/resources/shared-resource-facilities